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pentobarbital will lower the extent or result of tamoxifen by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Monitor.pentobarbital will reduce the extent or impact of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with powerful CYP3A4 inducers is not advisablepentobarbital will l